Effortless Comfort Near NYC’s Top Healthcare Facilities

Experience your own Park Avenue pied-à-terre at Hotel 48LEX, where modern luxury meets the welcoming ambiance of a sophisticated guesthouse. Nestled in Manhattan's Midtown East neighborhood, our boutique hotel blends high-style accommodations, signature amenities, and impeccable service for a luxe, personalized experience.

Whether you're visiting New York City for medical treatment or supporting a loved one, Hotel 48LEX offers a serene escape that feels like home. Our thoughtfully designed spaces and attention to detail ensure an atmosphere that puts you at ease-no matter how long your stay.

Neighborhood

Healthcare Centers

Close to New York's Leading Hospitals

One of the most convenient aspects of Hotel 48LEX is its proximity to the city's premier healthcare institutions. We make it easy for guests to access top medical facilities while enjoying an opulent, home-like refuge.

NYU Langone Health 1.4 miles
Memorial Sloan Kettering (MSK) 1.5 miles
New York-Presbyterian/Weill Cornell Medical Center 1.6 miles
Hospital for Special Surgery Main Hospital - 1.7 miles
The Mount Sinai Hospital 3.2 miles

To support those seeking care or providing support, we offer special rates through the links below:

For guests visiting NYU Langone Health, book here.
For guests visiting Memorial Sloan Kettering, book here.
For guests visiting New York-Presbyterian/Weill Cornell Medical Center, book here.
For guests visiting Hospital for Special Surgery, book here.
For guests visiting Mount Sinai, book here.
For general healthcare visits, book here.

Signature Amenities for Your Relaxation

Hotel 48LEX offers an array of amenities to ensure your stay is as tranquil and effortless as possible.

House Privileges:

Morning and afternoon self-serve coffee in The Lounge
Evening wine from 5 7 PM
Two bottles of water per guest room
$25 breakfast credit at Brasserie Cognac, including coffee, tea, and juice (additional fees may apply)
Premium Wi Fi access
Complimentary shoe-shine service
Laundry service

Wellness and Convenience:

Fully equipped fitness center with Peloton and Tonal machines
Pet-friendly accommodations
In-room umbrellas for unexpected weather
Business-tailored amenities and creative meeting spaces
A Bespoke, Homelike Haven :
At Hotel 48LEX, we believe that true hospitality goes beyond providing a place to stay-it's about delivering an experience that reflects the ease and warmth of home.
No matter the length of your stay, our attentive service and inviting surroundings provide the perfect balance of care and luxury.
Welcome to Your New York Home Away from Home.

Elegant Accommodations With a Residential Touch

Our rooms and suites are crafted with both elegance and restfulness in mind, offering a peaceful retreat that feels effortlessly chic. Meticulously appointed with upscale amenities and curated touches, each space exudes a sense of calm and understated luxury, reminiscent of a residential hideaway.

Spacious, Quiet Rooms: A sanctuary from the city's bustle, designed for ultimate relaxation.
Suites for Families & Friends: Ideal for those traveling with companions.
Modern Conveniences: Nespresso machines, microwaves, dishwashers, steamers, hair dryers, full-sized bath amenities, shoe-shine service, and same-day laundry and dry-cleaning service.
Home-Like Comforts: Egyptian cotton towels, dimmable bedside lighting, and an in-room safe.
Technology at Your Fingertips: TVs, workspace, and charging ports for all your devices.

For questions or further assistance, please contact [email protected]